A simple method for the electrophilic cyanation of secondary amines.
نویسندگان
چکیده
Bleach oxidizes trimethylsilyl cyanide to generate an electrophilic cyanating reagent that readily reacts with an amine nucleophile. This oxidative N-cyanation reaction allows for the preparation of disubstituted cyanamides from amines without using highly toxic cyanogen halides.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 16 1 شماره
صفحات -
تاریخ انتشار 2014